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Retinaldehyde (Retinal) is the most powerful Vitamin A derivative which is only one step away from retinoic acid. It is characterized by having great antioxidant properties; therefore, it has the ability to protect the body's cells from free radicals, which are the main cause of premature aging. Retinaldehyde LipoVes® is a science-driven skincare active developed under biotechnology backgrounds which contains stable liposomated Retinal. Its liposomal delivery system stabilizes the active ensuring potential benefits. It also penetrates the active into inner layers of the skin (approximate particle size of less than 20nm), maximizes its efficacy and reduces its irritation. Retinaldehyde Lipoves® is a stable vegan liposomal solution which acts 11 times faster than Retinol. The smaller the particle size, the deeper the penetration and the higher the efficacy.
- Induces biosynthesis of collagen in the skin
- Remodels the epidermis and dermis
- Provides anti-inflammatory and anti-oxidant properties
- Chemically exfoliates and lightens the skin
- Balances oil production in acne skins
In the body, we convert Beta Carotene into Retinol, Retinol into Retinaldehyde and Retinaldehyde into Retinoic Acid. Retinaldehyde is substantially more active (500 times more!) than their Vitamin A counterparts and Retinal is 1 step away from Retinoic Acid without the side effects of the Acid. All Vitamin A derivatives have important and proven activity in the skin in an escalating level from Beta Carotene to Retinoic Acid respectively. Retinaldehyde's known benefits are that it exfoliate and lighten the skin, reduces oil and bacteria, remodels the epidermis/dermis by actively stimulating collagen/elastin production and provides anti inflammatory and anti oxidant properties.
Bakuchiol is a plant-derived compound that has gained popularity in the skincare industry as a natural alternative to retinol. Retinol, a form of vitamin A, is known for its anti-aging properties, but it can also cause irritation and sensitivity in some individuals. Bakuchiol, on the other hand, is derived from the seeds of the Psoralea corylifolia plant, also known as babchi, and is considered a gentler option. Like retinol, bakuchiol has anti-aging properties, including reducing the appearance of fine lines and wrinkles, improving skin elasticity, and promoting collagen production. Unlike retinol, bakuchiol does not cause photosensitivity, meaning it can be used during the day without increasing the risk of sun damage. This makes it a suitable option for daytime skincare routines.
By ensapsulation of Bkuchiol with nano liposomes the Bakuchiol LipoVes are formed. Bakuchiol LipoVes with an approximate particle size of less than 20nm are penetrating deep into the skin and more effectively.
A hero ingredient to restore any unhealthy skin and essential support to skin's moisture barrier, especially valuable for dry, sensitive, and aging skin. Tetra-Ceramide LipoVes® combines four ceramide types (NS, NP, AP, and EOP) in a structure closely matching the skin’s natural ceramide composition, enhancing the skin's moisture barrier and preventing dryness. The formula improves skin hydration, elasticity, firmness, and reduces redness, significantly restoring skin health. Its effectiveness includes visibly reducing fine lines and supporting skin resilience against environmental stressors.The ingredient is water-soluble and oil-dispersable. In summary, Tetra-Ceramide LipoVes® offers an innovative, clinically proven approach to support skin barrier function and hydration, aligning with modern skincare trends focused on barrier repair and anti-aging.
Lactobionic acid is a polyhydroxy acid (PHA), derived from lactose, which is a sugar found in milk. It is distinguished by its larger and gentler molecularstructure compared to AHAs and BHAs. Due to its larger molecular size, Lactobionic acid forms a film on the skin's surface, reducing water loss and increasing hydration. It does not penetrate the skin, so it is an excellent ingredient for exfoliating and skin conditioning sensitive skin. Its primary advantages are predominantly associated with enhancing skin moisturization, promoting a more uniform tone, and improving overall clarity.
Hesperidin Methyl Chalcone (HMC) is a powerful flavonoid sourced from 100% natural upcycled pomelos. It improves skin functions by controling epidermal permeability and anti-inflammatory issues. Upcycled Hesperidin Methyl Chalcone (HMC) is a bioactive compound derived from pomelo (citrus fruit) waste, known for its strong antioxidant properties and benefits for sensitive skin. HMC exhibits antioxidant, anti-inflammatory, and capillary-strengthening properties. It improves the skin's barrier function, aids hydration, and is used to treat sensitive skin, rosacea, and dark circles under the eyes. It is used in skincare products designed specifically for sensitive or irritated skin, the eye area, and inflammatory skin conditions. HMC remains stable when exposed to light, making it a durable and effective ingredient. The production process uses biotechnological methods to reduce environmental impact. Waste products are repurposed in production.The sustainability and efficacy of HMC, particularly in caring for sensitive and damaged skin are its main features.
Improves skin balance:
Improves skin functions:
HMC can also be used in eye contour care. In the area around the eyes, the skin is thinner and more delicate, and the capillaries may be more prone to dilation or rupture, which can result in the appearance of dark circles or bags.HMC helps strengthen the capillaries, reduces inflammation and improves blood circulation in the area, thus contributing to a fresher and rejuvenated appearance:
Acetyl Hexapeptide-8 is a synthetic peptide with neurotransmitter-inhibiting properties which serves an anti-aging purpose in skincare products. Comprising six amino acids linked together, this peptide is recognized for its efficacy in reducing the visibility of wrinkles and fine lines by inhibiting specific muscle movements. It is believed to work similarly to Botox but without the need for injections. Acetyl Hexapeptide-8 enhances the appearance of expression lines, reduces muscle stiffness, and diminishes expression wrinkles. It is believed to interfere with the signals responsible for muscle contractions, leading to a temporary smoothing effect on the skin.
Acetyl Hexapeptide-38 is a synthetic peptide composed by six amino acids mainly focused on the increasing of breast volume. Stimulates adipogenesis and lipogenesis, thereby increasing the thickness of adipose tissue and lipid accumulation, resulting in a fuller and firmer skin. This peptide serves as an outstanding active ingredient for shaping the body by enhancing local volume where needed. It acts as a volume booster, capable of increasing local volume and reversing age-related volume losses. This makes it an essential component in replenishing treatments to apply on the neck, décolletage, face, breasts, and buttocks.
Acetyl Octapeptide-3 is a synthetic peptide composed by eight amino acids used for skin care products for its anti-aging purpose. It works by disrupting the release of neurotransmitters responsible for signaling muscle contractions. By reducing muscle activity, it aims to minimize the appearance of wrinkles and fine lines, particularly those resulting by daily facial expressions. Functioning in a manner that mimics the mechanism of Botox, its incorporation into skincare products is designed to provide users with a non-invasive option to address the visible signs of aging, contributing to a smoother and more youthful-looking complexion face.
Acetyl Tetrapeptide-5 is a synthetic peptide specifically formulated to address concerns commonly associated with the sensitive and delicate eye area. Possesses potential properties that can effectively diminish puffiness and under-eye bags. Furthermore, contributes to enhance skin elasticity and firmness in the eye contour. The mechanism of action of Acetyl Tetrapeptide-5 is intricately linked to its influence on factors associated with fluid balance and inflammation. By modulating these crucial elements, the peptide aims to create a harmonious environment that fosters a more refreshed and rejuvenated appearance in the eye area. This multifaceted approach underscores its commitment to not only addressing visible concerns but also contributing to the long-term resilience and vitality of the delicate skin around the eyes.
Alpha-Arbutin highlights its effectiveness and advantages as a skin-lightening agent. In a four-week skin-lightening study on 80 participants, Alpha-Arbutin at 1% concentration showed greater skin lightening compared to Kojic Acid, Beta-Arbutin, and Hydroquinone.Alpha-Arbutin’s alpha-glucoside bond structure enhances its affinity for tyrosinase, making it over ten times more effective at inhibiting tyrosinase than Beta-Arbutin. Alpha-Arbutin inhibits tyrosinase, an enzyme crucial in melanin production, leading to a lighter, more even skin tone. It also reduces tanning after UV exposure and minimizes the appearance of liver spots. It is recommended for skin-lightening products, age spot treatments, and BB/CC creams, with suggested concentrations of up to 2% for face and neck products.Alpha-Arbutin is scientifically validated to provide superior skin lightening at low concentrations, offering inhibitory effect on tyrosinase compared to Beta-Arbutin, thus supporting a brighter, more even skin tone.
Alpha-lipoic acid (ALA) serves as a potent scavenger with anti-inflammatory properties, enhancing the clinical characteristics of the skin, particularly addressing roughness caused by photoaging. Simultaneously, its powerful antioxidant nature directly scavenges a wide range of reactive oxygen species (ROS), offering protection to human keratinocytes against oxidative damage induced by UV exposure. This versatile compound interacts effectively with both water and lipid-soluble antioxidants, thereby reinforcing the antioxidant defense network. Furthermore, when combined with liposomes, alpha-lipoic acid contributes valuable raw materials for skin regeneration by replenishing lipid molecules and maintaining optimal moisture levels.
Ascorbyl glucoside is a stable derivative of Ascorbic Acid produced by the enzymatic bonding of a glucose molecule to the hydroxyl radical at C-2 of Vitamin C. When applied to the skin, it hydrolyzes into Vitamin C and Glucose by α-glucosidase, an enzyme naturally present in cell membranes. This natural enzyme releases Ascorbic Acid, which is assimilated by membrane transporters, exerting the same biological antioxidant activity in the body as the original Vitamin C. Unlike Ascorbic Acid, which requires an acidic pH to stabilize and penetrate the dermal layer, Ascorbyl Glucoside remains stable for extended periods at the skin's pH of 5,5. Ascorbyl glucoside has a great importance because of its safety, stability, and well-established release mechanism.
Azelaic acid is commonly used in the treatment of acne, melanoma, rosacea and cutaneous hyperpigmentation disorders. Azelaic acid has anti-inflammatory, antibacterial and anti-keratinization effects, and has a significant efficacy on acne. Its anti-inflammatory effect is through inhibition of nuclear transcription factors, thereby reducing the inflammatory cascade of different cytokines. Its antibacterial activity reduces the growth of bacteria such as P. acnes and Staphylococcus epidermidis in the follicle. Its keratolytic activity returns to normal the disordered growth of the skin cells lining the follicle. It is also a scavenger of free radicals and reduces inflammation.
Azelaic acid is commonly used in the treatment of acne, melanoma, rosacea and cutaneous hyperpigmentation disorders. Azelaic acid has anti-inflammatory, antibacterial and anti-keratinization effects, and has a significant efficacy on acne. Its anti-inflammatory effect is through inhibition of nuclear transcription factors, thereby reducing the inflammatory cascade of different cytokines. Its antibacterial activity reduces the growth of bacteria such as P. acnes and Staphylococcus epidermidis in the follicle. Its keratolytic activity returns to normal the disordered growth of the skin cells lining the follicle. It is also a scavenger of free radicals and reduces inflammation.
Bakuchiol is a plant-derived compound that has gained popularity in the skincare industry as a natural alternative to retinol. Retinol, a form of vitamin A, is known for its anti-aging properties, but it can also cause irritation and sensitivity in some individuals. Bakuchiol, on the other hand, is derived from the seeds of the Psoralea corylifolia plant, also known as babchi, and is considered a gentler option. Like retinol, bakuchiol has anti-aging properties, including reducing the appearance of fine lines and wrinkles, improving skin elasticity, and promoting collagen production. Unlike retinol, bakuchiol does not cause photosensitivity, meaning it can be used during the day without increasing the risk of sun damage. This makes it a suitable option for daytime skincare routines.
By ensapsulation of Bkuchiol with nano liposomes the Bakuchiol LipoVes are formed. Bakuchiol LipoVes with an approximate particle size of less than 20nm are penetrating deep into the skin and more effectively.
Betaine salicylate is an ingredient composed by betaine, a naturally occurring amino acid derivative, with salicylic acid, a beta hydroxy acid (BHA). This mixture combines de advantages of its skinconditioning and exfoliating properties in just one ingredient. With remarkable exfoliating properties, it effectively eliminates dead skin cells, unclogs pores, and enhances skin texture. This renders it particularly advantageous in addressing concerns like acne, blackheads, and uneven skin tone.
Biotin also known as vitamin H or coenzyme R is a water-soluble vitamin B7 (Vitamin H), often recommended for healthy hair. Since biotin deficiency can lead to thinning of the hair, proponents claim that washing your hair with biotin-enriched shampoo can thicken the hair and stimulate hair growth.
Biotinoyl Tripeptide-1 is a cosmetic ingredient which stimulates the metabolism of hair follicle cells specifically targeting hair growth and volume. Through its synergistic combination with biotin, the peptide’s functionality is further enhanced. Biotin is an essential vitamin which plays a crucial role in maintaining the health of hair, improving so its strength and condition. As a result, the hair feels softer and smoother giving it a stronger and healthier appearance.
Bismuth Oxychloride is silver scaly corpuscle, which is found naturally in the rare mineral bismoclite. Bismuth is a heavy and brittle metal, whereas bismuth oxychloride is a pigment that comes in either a pearl or diamond finish , and is used to give mineral makeups either a matter or shimmery appearance. It’s also found in bronzers , blush and eye shadows because of its ability to create a shimmery look , and to give a silky feel , as well as because it helps the minerals adhere to the skin.
Diaminopyrimidine Oxide is a chemical compound that is used to increase the volume of hair specifically the hair that is in the growth stage. Compared with minoxidil, no effect on blood pressure and better safety. It is used commonly in all types of hair products from shampoo to conditioner, lotions, gels, serums, sprays & oils. It can also be found in eyelash products & products for the eyebrows as well as eyeliners & mascaras.Diaminopyrimidine Oxide benefits:- Promoting keratin fiber production to increase hair volume- Softens the collagen fiber network to prevent hair loss- Boost the optimises hair growth cycle, accelerates hair growth- Make fine hair grow healthily and strengthen hair- Prevents follicle clogging and firmly the hair from root to tip
Ceramides are a class of lipids naturally present in the epidermis, playing a crucial role in cell cohesion to establish a robust barrier against moisture loss. This barrier is essential for shielding the skin, preventing dryness, and preserving tissue hydration so they are a crucial ingredient for maintaining the skin's barrier function. As a molecule identical to naturally present in human skin, Ceramide IIIB is exceptionally well-suited for providing prolonged long-term protection and support for the recovery of sensitive and dry skin promoting skin comfort.
Ubiquinone is a potent anti-aging ingredient with high antioxidant properties. It helps neutralize free radicals in the skin. By scavenging these free radicals, Ubiquinone helps protect the skin from oxidative damage such as UV radiation, pollution, and environmental stressors which can contribute to premature aging. Due to its role in energy production within cells, Ubiquinone supports cellular functions and promotes skin vitality reducing the appearance of fine lines and wrinkles, improving skin elasticity and maintaining a youthful complexion.
Copper tripeptide-1 is a small protein composed of the three amino acids glycine, histidine, and lysine combined with the physiologically beneficial mineral copper. Functioning as an anti-aging and as a hair growth stimulating ingredient, increases keratinocyte proliferation and facilitates the synthesis of collagen, a fundamental protein in skin’s structure. This dual action leads to an enhanced skin elasticity and a reduction of wrinkles, fortifying the protection for the skin's barrier function.
Curcumin, the active compound derived from the rhizome of Curcuma longa, found in turmeric, offers potential skincare benefits. Renowned for its anti-inflammatory effects, it can soothe irritated skin, reduce redness, and alleviate discomfort. Its anti-inflammatory properties position curcumin as a valuable ingredient in skincare products designed to address acne and sensitive skin. Furthermore, its antiseptic and antibacterial qualities make it effective in preventing acne-causing bacteria growth, contributing to faster healing by soothing already inflamed areas. Incorporating curcumin into skincare formulations may also help protect the skin from oxidative stress caused by environmental factors like UV radiation and pollution contributing to a brightening and more even skin tone.
D-Panthenol is the pro-vitamin of D-Pantothenic acid (Vitamin B5) for use in hair, skin and nail care products. It acts as a skin conditioning agent to provide deep penetrating moisture to the skin, stimunlating epithelisation to provide long lasting moisture to hair, preventing damage, thicken hair and improve luster and sheen. This product can also be used in nail careproducts to improve hydration and impart flexibility.
Dermal Papilla Pro LipoVes is designed for hair care with a focus on combatting hair loss through advanced cosmetic formulation techniques. Diaminopyrimidine Oxide and Pyrrolidinyl Diaminopyrimidine Oxide as active ingredients focus on hair biology and common hair loss types, especially androgenetic alopecia (AGA), caused by DHT’s effects on hair follicles.Challenges in existing anti-hair loss products, such as low efficacy, limited bioavailability, and side effects. Dermal Papilla Pro LipoVes utilizes flexible liposome carriers to enhance ingredient delivery into hair follicles, increasing bioavailability and promoting hair growth. Experiments demonstrate that Dermal Papilla Pro LipoVes promotes hair follicle cell health, reduces oxidative stress, and supports collagen production, leading to significant hair growth improvements. It is non-irritating and safe for application on human skin.Dermal Papilla Pro LipoVes has an unique formulation for effective hair growth, utilizing advanced nanotechnology for enhanced ingredient delivery and a stronger anti-hair loss effect.
Tripeptide-3, also named dipeptide diaminobutyroyl benzylamide diacetate, mimics the effect of waglerin-1, a peptide that is found in the venom of the viper Tropidolaemus Wagleri. Waglerin-1 has been shown to block the nicotinic acetylcholine receptors at the neuromuscular junction, thus inhibiting muscular movement. The function of the Wagerlin-1-mimicking peptide is important for the treatment of lines since facial areas associated with repeated muscle movement are especially susceptible to wrinkle formation.
Ectoine is considered an osmolyte for skin, Ectoine helps maintain balanced hydration by maintaining the correct water balance in skin. In doing so, skin can better maintain a smooth, soft surface. Newer research indicates Ectoine can also help protect skin from environmental stressors related to differenttypes of natural light and pollutants. This believed to happen in part because of its antioxidant ability as wellas what seems to be a natural ability to protect skin from dehydration due to environmenta exposure.
Ethyl Ascorbic Acid is a high stable derivative of ascorbic acid, which is a form of Vitamin C which does not need the action of any enzyme to activate. This compound is commonly used in skincare products due to its ability to provide the benefits associated with Vitamin C. One of the main advantages of Ethyl Ascorbic Acid is its stability; unlike pure Ascorbic Acid, which can be prone to oxidation when exposed to air and light, Ethyl Ascorbic Acid is more stable, allowing for a longer shelf life and improved efficacy in skincare formulations. Recognized for its potent antioxidant properties, Ethyl Ascorbic Acid plays a vital role in promoting collagen synthesis, brightening the skin, and safeguarding against environmental damage. The result is a more uniform and radiant skin tone. This compound has become a valued inclusion in skincare routines, providing a reliable and enduring solution for individuals seeking the transformative effects of Vitamin C with heightened stability.
Ethyl Ascorbic Acid is a stable Vitamin C derivate with excellent skin brightening activity. Ist chemical structure is unique. Ethyl Ascorbic Acid is a powerful inhibitor of melanogenesis. It has excellent skin brightening activity and is much higher stabel than other ascorbic acid erivatives. It has a fast long-lasting effect.
Ferulic acid, renowned for its potent antioxidant properties, plays a crucial role in safeguarding the skin's structures. Beyond its photoprotective function that slows down skin photoaging, it actively contributes to overall skin brightening. Concurrently, ferulic acid demonstrates efficacy in reducing fine wrinkles, offering a dual benefit for skin texture improvement. Adding to its appeal are various physiological functions, including anti-inflammatory, antioxidant, and antimicrobial activities. This versatile compound emerges not just as a defender against environmental stressors but also as a contributor to the refinement and rejuvenation of the skin, providing a holistic approach to skincare.
Genistein, an isoflavone derived from soy, has exhibited promising outcomes in the development of anti-aging cosmetic formulations, specifically targeting skin elasticity and photoaging. This compound, found in soybeans, is gaining recognition for its potential to prevent age-related skin changes accelerated by menopause. Various studies have highlighted Genistein's capacity to significantly increase collagen thickness and fortify skin breaking strength. These findings suggest that Genistein holds promise as an effective alternative therapy for addressing age-related skin changes, particularly in postmenopausal women. Additionally, its anti-oxidant properties consistently demonstrate effectiveness in alleviating skin dryness, diminishing wrinkles, and restoring the disrupted architecture of the skin.
Glabridin is a natural compound found in licorice (Glycyrrhiza glabra) root extract which has been used for centuries in traditional medicine. Glabridin is known for its skin-brightening properties as it inhibits the enzyme tyrosinase, which is involved in the production of melanin, the pigment responsible for skin color. By reducing melanin production, Glabridin may help in preventing and lightening dark spots and hyperpigmentation. As an antioxidant, Glabridin helps protect the skin from oxidative stress caused by free radicals contributing to the prevention of premature aging and damage to the skin cells.
Glycolic acid is an alpha hydroxy acid (AHA) known for its chemical exfoliating properties. It works by exfoliating the outermost layer of the skin, promoting the shedding of dead skin cells. This helps to unclog pores, refine skin texture, and encourage the emerge of a fresher and more radiant skin. Due to this exfoliating action, glycolic acid proves effective in addressing hyperpigmentation and dark spots obtaining a uniform skin tone. It is well incorporated into antiacne skincare routines for its ability to prevent and treat acne also reducing the appearance of acne scars by promoting cell turnover.
Guaiac Blue LipoVes® is an encapsulated natural anti-inflammatory ingredient with repairing function. Guaiac Blue LipoVes® contains encapsulated Guaiazulene, a naturally occurring compound from the azulene family, extracted from chamomile plant and appears in deep blue color. Guaiac Blue LipoVes®, an encapsulated version of guaiazulene, ensures water solubility and enhanced stability against external factors. So it is a stable natural active with colorant properties. It helps calm irritation, reduces redness and promotes healing. Its gentle properties make it ideal for sensitive skin products, particularly those designed to soothe and repair.It participates in the three phases of skin repair:1. Innflammation: Inhibition of prostagrandin production by blocking cyclooxygenase and modulation of proinflammatory cytokines.2. Regeneration: Proliferation by reducing excessive inflammation and protecting endothelial cells3. Reparation: Enzymatic regulation by influencing the activity of matrix metalloproteinase to ballance collagen degeneration and synthesis and antioxidant propperties.
Hyaluronic Acid is a powerful moisturizer & humectant, it providers smoothness & softening to the skin. Its excellent anti-wrinkle effects, promotes growth of new skin cells after peelings, supports wound healing. Hyaluronic Acid with low molecular weight enhances skin penetration, allowing it to reach deeper layers for more effective hydration compared to higher molecular weight hyaluronic acid. This form of HA binds to moisture within the skin, offering prolonged hydration.Skin Elasticity & Firmness: Regular use improves elasticity, helping to reduce the appearance of fine lines and wrinkles.It enhances the skin’s natural barrier, providing resilience against environmental factors. Hyaluronic Acid is ideal for formulations in creams, serums, and other skincare products aimed at anti-aging, hydration, and skin repair. Sodium Hyaluronate LMW-HA provides enhanced, deeper moisturization, making it a valuable addition to skincare products designed for intensive hydration and anti-aging benefits.
Hydroxypinacolone Retinoate, a derivative of retinoic acid and a form of vitamin A, is recognized for its potential to deliver similar advantages as retinoids but with notable advantages. Its main strength lines in its reduced propensity for irritation and enhanced stability. Unlike certain other retinoids, it is less susceptible to degradation when exposed to air and light. It offers anti-aging and skin-renewing benefits attributed to vitamin A derivatives. By stimulating collagen production and promoting skin renewal, it actively diminishes the appearance of fine lines and wrinkles. Additionally, Hydroxypinacolone Retinoate may contribute to addressing hyperpigmentation concerns. Its favorable stability and potential to provide skincare benefits make it a noteworthy ingredient in cosmetic formulations.
Hydroxypinacolone Retinoate, a derivative of retinoic acid and a form of vitamin A, is recognized for its potential to deliver similar advantages as retinoids but with notable advantages. Its main strength lies in its reduced propensity for irritation and enhanced stability. Unlike certain other retinoids, it is less susceptible to degradation when exposed to air and light. It offers anti-aging and skin-renewing benefits attributed to vitamin A derivatives. By stimulating collagen production and promoting skin renewal, it actively diminishes the appearance of fine lines and wrinkles. Additionally, Hydroxypinacolone Retinoate may contribute to addressing hyperpigmentation concerns. Its favorable stability and potential to provide skincare benefits make it a noteworthy ingredient in cosmetic formulations.
L-Carnitin Base is an amino acid that can be produced by the body itself and is used for energy metabolism in cells and for the transport of fatty acids. Carnitine is considered a natural fat killer and is used as an active ingredient primarily in products to combat cellulite.
L-Carnosine, also known simply as Carnosine, is a dipeptide molecule composed of two amino acids: beta-alanine and histidine, naturally present in various tissues of the body. It is an historically known peptide for its powerful different antioxidant properties being the focus of numerous studies. Research indicates that it plays a protective role against glycation, thereby preventing cellular damage and contributing to the improvement of skin texture and appearance reducing roughness and expression lines. As an intriguing and potent ingredient, L-Carnosine holds promise for incorporation into any anti aging product.
The cellular defense against reactive oxygen species relies on antioxidant enzymes and small molecules. L-ergothioneine, a powerful antioxidant obtained from the diet, accumulates in cells exposed to high oxidative stress. Its protective role depends on the L-ergothioneine-specific receptor/transporter OCTN1, as it cannot permeate the plasma membrane.
L-Glutathione plays an important role in preventing oxidative damage to the skin In addition to its many recognized biological functions, glutathione has also been associated with skin lightening ability. Glutathione utilizes different mechanisms to exert its action as a skin whitening agent at various levels of melanogenesis. Key features of L-Glutathione are smoothing and whitening, lightening dark spots, anti-aging and anti-wrinkles and nourishing the skin.
Lactobionic acid is a polyhydroxy acid (PHA), derived from lactose, which is a sugar found in milk. It is distinguished by its larger and gentler molecularstructure compared to AHAs and BHAs. Due to its larger molecular size, Lactobionic acid forms a film on the skin's surface, reducing water loss and increasing hydration. It does not penetrate the skin, so it is an excellent ingredient for exfoliating and skin conditioning sensitive skin. Its primary advantages are predominantly associated with enhancing skin moisturization, promoting a more uniform tone, and improving overall clarity.
Magnesium Ascorbyl Phosphate is a water-soluble stabilized salt of Ascorbic Acid. Unlike some forms of vitamin C that require an acidic pH for activation, Magnesium Ascorbyl Phosphate is effective in a more neutral pH range, between 5-7, making it more suitable for sensitive skin. It is used due to its inhibitory effects on melanogenesis, free radical scavenger activity and collagen stimulation. This form of Vitamin C is a robust choice to ensure stability in the formulation.
Mandelic acid is an alpha hydroxy acid (AHA) that boasts remarkable exfoliating and skin-renewing properties. Distinguished by its larger molecular size, this AHA exhibits a gentler penetration into the skin, rendering it particularly suitable for individuals with sensitive skin. Like other AHAs, mandelic acid facilitates exfoliation by promoting the shedding of dead skin cells. This process effectively unclogs pores, refines skin texture, and impart a notably smoother appearance upon the skin. It also has antibacterial properties, making it beneficial for individuals with acne-prone skin reducing the growth of acne-causing bacteria.
Myristoyl Pentapeptide-17 is a potent ingredient renowned for its role in promoting eyelash growth. Its mechanism of action involves stimulating the expression of the keratin gene, a pivotal factor in the structural integrity of hair. This stimulation results in the increased proliferation of keratinocytes within the hair bulb, a crucial region for the development and nourishment of hair follicles. Myristoyl Pentapeptide-17 manifests its efficacy by imparting a dual benefit of both thickening and lengthening eyelashes. This transformative action contributes to an overall stronger and more voluminous appearance of the eyelashes, making it a highly sought-after ingredient for inclusion in eyelash serums and other formulations targeted at enhancing lash beauty.
Vitamin B3 improves the skin barrier, has whitening and antiaging properties and acts against acne and skin blemishes. Niacinamide is the water-soluble amide of nicotinic acid. It is increasingly used in cosmetics, topical creams and supplements for its aid in fading age spots and hyper-pigmentation, reducing fine lines and wrinkles, and improving elasticity.
Palmitoyl hexapeptide-12 offers promising anti-aging benefits for the skin as it has been developed to stimulate elastin synthesis by promoting the stimulation of collagen production. It stimulates collagen and elastin fibroblasts, as well as develops glycosaminoglycans and fibronectin. The intracellular mechanism refers to the way in which it can reduce the production of proinflammatory mediators (IL1, IL-6, and IL-8) and ultimately slow down the skin matrix’s degradation leading to improved skin aging signals. Consequently, Palmitoyl Hexapeptide-12 is highly valued as a sought-after ingredient in antiaging skincare formulations.
Palmitoyl Pentapeptide-4 is a powerful booster of collagen, crucial for keeping the skin firm and elastic. It works by restructuring the skin and is especially effective in increasing collagen types I, III, and IV, as well as fibronectin and glycosaminoglycans. Palmitoyl Pentapeptide-4 contains a key component, proline, which, when converted to hydroxyproline, directly influences collagen synthesis. This ingredient is known for reducing wrinkles and fine lines, making it a popular choice for addressing signs of aging. By supporting collagen production, Palmitoyl Pentapeptide-4 helps improve skin firmness, counteracting the natural loss of collagen that comes with aging.
Palmitoyl Tetrapeptide-7, also known as Palmitoyl Tetrapeptide-3, is a short chain of four amino acids: glycine, glutamine, proline, and arginine. This peptide is often used in anti-aging skincare products because it not only stimulates collagen production, but also reduces IL-6 secretion and inflammation calming the skin of external effects such sun exposure and pollution. By promoting collagen production, Palmitoyl Tetrapeptide-7 helps minimize the appearance of fine lines and wrinkles, leading to a smoother and more youthful complexion.
Palmitoyl tripeptide-1 is a peptide that has shown the ability to stimulate collagen synthesis in a human fibroblast culture and prevent its degradation after the exposure to UVA light. It promotes the production of elastin, hyaluronic acid, glycosaminoglycan, and fibronectin with a visible reduction of wrinkles in terms of length, depth, and roughness. Comparable to retinoic acid with regards to its activity, it does not trigger irritation. Collagen and glycosaminoglycan synthesis are stimulated, the epidermis is reinforced, and wrinkles are diminished.
Palmitoyl Tripeptide-5 is a potent anti-aging ingredient that mimics the effects of thrombospondin-1 (TSP-1), an extracellular matrix protein naturally present in the body. TSP-1 is known for enhancing the activity of transforming growth factor beta (TGFβ), which plays a crucial role in promoting collagen production. The persistent increase in Type I and Type III collagen levels produced by dermal fibroblasts, along with the prevention of collagen degradation, contributes to the peptide's efficacy. By supporting collagen synthesis and inhibiting degradation, Palmitoyl Tripeptide-5 helps reduce the appearance of fine lines and wrinkles, making it a valuable component in skincare formulations designed for rejuvenation and anti-aging benefits.
An unsung hero for a healthy skin barrier. Phytospingosine strengthens the outermost layer of the skin and is very well tolerated and has a wide range of applications. The outermost layer of our skin is responsible for not only keeping moisture from getting out, but also irritants and toxins from getting in. Thus when the barrier is compromised or weakened, unwanted factors can get in, resulting in all kinds of issues from redness to rashes. As well for acne vulgaris different pathogenic factors contribute to the inflammation process. Studies confirmed the strong anti microbial and anti inflammatory activity and the efficassy of phytospingosine adressing acne vulgaris. It strengthens the skin barrier so moisture is kept in and irritants are not let in. It triggers the production of natural moisturizing factors and delivers anti-inflammatory and antibacterial effects.
Phytospingosine is COSMOS registered and is used at levels from 0.1 to 1%
γ-PGA is long-lasting moisturazing and endogenous hydrating. PGA Na is a natural, multi-functional and biodegradable biopolymer produced from L-glutamic acid through a fermentation process with a Bacillus subtilis. It is a water-soluble homo-polyamide consisting of D-glutamic acid and L-glutamic acid monomers connected by amide linkages between α-amino and γ-carboxyl groups.
Resveratrol is a potentially known antioxidant with great anti-aging properties. As an antioxidant, Resveratrol helps protect the skin from oxidative stress caused by free radicals. This oxidative stress can contribute to premature aging, including the development of fine lines, wrinkles, and other signs of aging. By neutralizing free radicals, Resveratrol supports the skin's defense against environmental and external damage. Its ability to inhibit tyrosinase, an enzyme involved in melanin production, may contribute to its skin-brightening effects. This can help address hyperpigmentation and promote a more even skin tone.
Retinaldehyde (Retinal) is the most powerful Vitamin A derivative which is only one step away from retinoic acid. It is characterized by having great antioxidant properties; therefore, it has the ability to protect the body's cells from free radicals, which are the main cause of premature aging. Retinaldehyde LipoVes® is a science-driven skincare active developed under biotechnology backgrounds which contains stable liposomated Retinal. Its liposomal delivery system stabilizes the active ensuring potential benefits. It also penetrates the active into inner layers of the skin (approximate particle size of less than 20nm), maximizes its efficacy and reduces its irritation. Retinaldehyde Lipoves® is a stable vegan liposomal solution which acts 11 times faster than Retinol. The smaller the particle size, the deeper the penetration and the higher the efficacy.
- Induces biosynthesis of collagen in the skin
- Remodels the epidermis and dermis
- Provides anti-inflammatory and anti-oxidant properties
- Chemically exfoliates and lightens the skin
- Balances oil production in acne skins
In the body, we convert Beta Carotene into Retinol, Retinol into Retinaldehyde and Retinaldehyde into Retinoic Acid. Retinaldehyde is substantially more active (500 times more!) than their Vitamin A counterparts and Retinal is 1 step away from Retinoic Acid without the side effects of the Acid. All Vitamin A derivatives have important and proven activity in the skin in an escalating level from Beta Carotene to Retinoic Acid respectively. Retinaldehyde's known benefits are that it exfoliate and lighten the skin, reduces oil and bacteria, remodels the epidermis/dermis by actively stimulating collagen/elastin production and provides anti inflammatory and anti oxidant properties.
Retinoic Acid is the active form of Vitamin A, it directly binds to retinoid receptors in the skin cells and initiates biological responses. It exhibits numerous anti-aging effects with highly effectiveness. By promoting collagen production, it effectively reduces the appearance of fine lines and wrinkles while also enhancing skin elasticity. Furthermore, its ability to stimulate the production of new healthy skin cells, leads to a smoother skin tone and texture, providing additional benefits in addressing hyperpigmentation.
Retinol is a precursor to retinoic acid and is a less active form of vitamin A. It is considered less potent than retinal as it requires conversion to retinal within the skin, and this conversion process limits its potency. Consequently, it tends to be milder and less irritating than retinal. It also offers exceptional anti-aging benefits reducing the appearance of fine lines, wrinkles and uneven skin tone, Retinol serves a crucial role in stimulating collagen production, thereby improving skin firmness and restoring elasticity. Its proactive integration with the skin's renewal process not only diminishes age spots but also refines overall texture, contributing to a more youthful and radiant complexion.
Retinol is a precursor to retinoic acid and is a less active form of vitamin A. It is considered less potent than retinal as it requires conversion to retinal within the skin, and this conversion process limits its potency. Consequently, it tends to be milder and less irritating than retinal. It also offers exceptional anti-aging benefits reducing the appearance of fine lines, wrinkles and uneven skin tone, Retinol serves a crucial role in stimulating collagen production, thereby improving skin firmness and restoring elasticity. Its proactive integration with the skin's renewal process not only diminishes age spots but also refines overall texture, contributing to a more youthful and radiant complexion.
Retinyl retinoate is a new vitamin A derivative with higher activity, obtained by the esterification reaction of the hydroxyl group of retinol and retinoic acid, while avoiding the limitations of retinol and retinoic acid in cosmetic applications; Retinyl retinoate retains the ring end group and side chain alkenyl group, still has the biological activity of retinol and retinoic acid, and its ability to promote skin regeneration is better than retinol and retinoic acid; It improves the optical stability and chemical stability of retinol, while reducing the irritation of retinol and retinoic acid.
Salicylic acid is a beta hydroxy acid (BHA) commonly used in skincare products for its exfoliating and anti-inflammatory properties. It is a highly popular ingredient in acne treatments as it effectively exfoliates the skin, by breaking down and loosening dead skin cells, resulting in a visibly smoother complexion. Beyond its exfoliating prower, salicylic acid has also anti-inflammatory properties that can help soothe irritated skin. This makes it a suitable choice for products with acne-prone or sensitive skin.
Salicylic acid is a beta hydroxy acid (BHA) commonly used in skincare products for its exfoliating and anti-inflammatory properties. It is a highly popular ingredient in acne treatments as it effectively exfoliates the skin, by breaking down and loosening dead skin cells, resulting in a visibly smoother complexion. Beyond its exfoliating prowess, salicylic acid has also anti-inflammatory properties that can help soothe irritated skin. This makes it a suitable choice for products with acne-prone or sensitive skin.
Sodium Ascorbyl Phosphate is a water-soluble stabilized salt of Ascorbic Acid. Esterification of ascorbic acid protects vitamin C from destruction by oxidation. Sodium Ascorbyl Phosphate is effective in a more neutral pH range, between 5-7, making it a good choice for sensitive skin products and stable to formulations. It provides antioxidant benefits and the ability to address skin concerns such as hyperpigmentation and aging. This form of Vitamin C is an interesting and secure choice to ensure stability in the formulation.
Sodium Hyaluronate is a powerful moisturizer & humectant, it providers smoothness & softening to the skin. Its excellent anti-wrinkle effects, promotes growth of new skin cells after peelings, supports wound healing. Sodium Hyaluronate with low molecular weight enhances skin penetration, allowing it to reach deeper layers for more effective hydration compared to higher molecular weight hyaluronic acid. This form of HA binds to moisture within the skin, offering prolonged hydration.Skin Elasticity & Firmness: Regular use improves elasticity, helping to reduce the appearance of fine lines and wrinkles.It enhances the skin’s natural barrier, providing resilience against environmental factors. Sodium Hyaluronate is ideal for formulations in creams, serums, and other skincare products aimed at anti-aging, hydration, and skin repair. Sodium Hyaluronate LMW-HA provides enhanced, deeper moisturization, making it a valuable addition to skincare products designed for intensive hydration and anti-aging benefits.
Transdermal empidermal growth factor (T-EGF) is an eco-friendly and highly efficient cosmetic active. It is the perfect booster ingredient for skin-repairing formulations, whether in a serum or a cream. This naturally occurring protein stimulates fibroblasts to produce collagen and elastin. T-EGF reduces redness in already low dosage (only 0.0002%). Transdermal Epidermal Growth Factor (T-EGF) has proven to be effective in repairing sensitive, dry and damaged skin. It reduces water loss and helps to hydrate the stratum corneum
A hero ingredient to restore any unhealthy skin and essential support to skin's moisture barrier, especially valuable for dry, sensitive, and aging skin. Tetra-Ceramide LipoVes® combines four ceramide types (NS, NP, AP, and EOP) in a structure closely matching the skin’s natural ceramide composition, enhancing the skin's moisture barrier and preventing dryness. The formula improves skin hydration, elasticity, firmness, and reduces redness, significantly restoring skin health. Its effectiveness includes visibly reducing fine lines and supporting skin resilience against environmental stressors.The ingredient is water-soluble and oil-dispersable. In summary, Tetra-Ceramide LipoVes® offers an innovative, clinically proven approach to support skin barrier function and hydration, aligning with modern skincare trends focused on barrier repair and anti-aging.
Tetrahydrocurcumin, a derivative of curcumin, the active compound in turmeric (Curcuma longa), is produced through the metabolic reduction of curcumin. This transformative process modifies the structure of curcumin, yielding a compound with distinct antioxidant and anti-inflammatory properties. Tetrahydrocurcumin plays a vital role in neutralizing free radicals which are highly reactive molecules that can induce oxidative stress and harm cells. By doing so, it effectively shields the skin from environmental damage, diminishes inflammation, and contributes to the promotion of a vibrant and healthy complexion.
THA is a plant-based alternative to standard hyaluronic acid. It has a superior water retention capacity and it is able to efficiently moisturize skin and hair. Ist softness also makes it a natural alternative to silicones. This power moisturizer not only promotes the growth of new skin cells, but it promotes collagen production that give it anti-aging properties.
Tri-Ceramide LipoVes® is the combination of Ceramide NP, Ceramide NS and Salicyloyl Phytoosphingosine which also plays a role in the structure and function of the skin's lipid barrier. Combining salicylic acid with phytosphingosine offers benefits related to both exfoliation and skin barrier support. The salicylic acid component may help with acne-prone skin, while phytosphingosine contributes to the overall health of the skin barrier. Has been demonstrated that the combination of those ingredients increases notably the moisturizing effect on the skin, improving barrier function and repairing skin’s barrier.
Hesperidin Methyl Chalcone (HMC) is a powerful flavonoid sourced from 100% natural upcycled pomelos. It improves skin functions by controling epidermal permeability and anti-inflammatory issues. Upcycled Hesperidin Methyl Chalcone (HMC) is a bioactive compound derived from pomelo (citrus fruit) waste, known for its strong antioxidant properties and benefits for sensitive skin. HMC exhibits antioxidant, anti-inflammatory, and capillary-strengthening properties. It improves the skin's barrier function, aids hydration, and is used to treat sensitive skin, rosacea, and dark circles under the eyes. It is used in skincare products designed specifically for sensitive or irritated skin, the eye area, and inflammatory skin conditions. HMC remains stable when exposed to light, making it a durable and effective ingredient. The production process uses biotechnological methods to reduce environmental impact. Waste products are repurposed in production.The sustainability and efficacy of HMC, particularly in caring for sensitive and damaged skin are its main features.
Improves skin balance:
Improves skin functions:
HMC can also be used in eye contour care. In the area around the eyes, the skin is thinner and more delicate, and the capillaries may be more prone to dilation or rupture, which can result in the appearance of dark circles or bags.HMC helps strengthen the capillaries, reduces inflammation and improves blood circulation in the area, thus contributing to a fresher and rejuvenated appearance:
Phloretin is a powerful antiaging ingredient sourced from 100% natural upcycled pomelos. Upcycled Phloretin is a natural antioxidant with skin whitening properties, derived from pomelo waste using sustainable and innovative technology. Waste pomelos are repurposed using an AI-assisted enzymatic process, reducing energy consumption and emissions. Phloretin neutralizes free radicals, protecting against oxidative damage, particularly from UV radiation. It also supports cellular health and reduces inflammation. Phloretin inhibits tyrosinase, an enzyme involved in melanin production, making it ideal for treating hyperpigmentation and promoting a more even skin tone. It reduces pro-inflammatory cytokines and molecules, which helps in treating acne and inflammation-related skin issues. Phloretin protects the skin from environmental damage, reducing fine lines and wrinkles, making it valuable in anti-aging creams. Its ability to inhibit melanin production makes it effective in skin brightening and treating uneven skin tones.
VC-IP Ascorbyl Tetraisopalmitate is a lipid-soluble and and non-oxiditable form derivative of Vitamin C. Being lipid-soluble, it demonstrates an enhanced ability to penetrate the skin's lipid barrier. This characteristic allows for deeper absorption, potentially leading to more effective delivery of Vitamin C into the skin cells. Once absorbed VC-IP Ascorbyl Tetraisopalmitate is converted into Vitamin C in the cells through an enzymatic reaction. VC-IP Ascorbyl Tetraisopalmitate shares some common benefits with other Vitamin C derivatives such a potential whitening and collagen producer. Its lipophilic nature and unique chemical structure give it distinct formulation characteristics.
Vitamin AEK LipoVes® complex is an excellent anti-ageing blend that combines three selected ingredients:Tocopheryl Acetate: Is a synthetic form of vitamin E, where tocopherol (Vitamin E) is combined with acetic acid to create Tocopheryl Acetate. This compound is known for its highly antioxidant properties, helping to protect the skin from the damaging effects of free radicals which contribute to premature aging and skin damage.Retinyl Palmitate: Retinyl palmitate is a synthetic form of Vitamin A, specifically a combination of retinol (Vitamin A1) and palmitic acid. It is a milder form of retinoid compared to retinol or retinoic acid which plays an anti-ageing role helping improve the appearance of fine lines and wrinkles.Vitamin K1 Oxide: Vitamin K is often associated with its potential to help reduce the appearance of dark circles under the eyes and bruises. Its oxide form is much more stable than the one is not.
Vitamin E stands out as the primary lipid-soluble antioxidant within the skin, playing a pivotal role in shielding against oxidative stress induced by free radicals. These free radicals, known for their potential to harm skin cells and accelerate the aging process, underscore the significance of Vitamin E in skincare. The inclusion of Vitamin E in cosmetic formulations is specifically designed to establish a robust protective barrier, guarding the skin against the effects of oxidative stress and promoting overall skin health.
Discover advanced cosmetic ingredients such as liposomal active ingredients and upcycled solutions. The scientifically developed active ingredients support antiaging, hydration and skin renewal and much more.
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